Chaos begets order: Asynchronous cell contractions drive epithelial morphogenesis Journal Article


Author(s): Paluch, Ewa; Heisenberg, Carl-Philipp
Article Title: Chaos begets order: Asynchronous cell contractions drive epithelial morphogenesis
Affiliation
Abstract: Apical cell contraction triggers tissue folding and invagination in epithelia. During Drosophila gastrulation, ventral furrow formation was thought to be driven by smooth, purse-string-like constriction of an actomyosin belt underlying adherens junctions. Now Martin et al. report in Nature that ventral furrow formation is triggered by asynchronous pulsed contractions of the apical acto-myosin cortex in individual cells.
Keywords: Transcription Factors; Drosophila Proteins; morphogenesis; Drosophila melanogaster; Body Patterning; Epithelium; Twist Transcription Factor
Journal Title: Developmental Cell
Volume: 16
Issue 1
ISSN: 1534-5807
Publisher: Cell Press  
Date Published: 2009-01-20
Start Page: 4
End Page: 6
DOI: 10.1016/j.devcel.2008.12.011
Open access: no