Non-canonical Wnt signalling and regulation of gastrulation movements Journal Article


Author(s): Tada, Masazumi; Concha, Miguel L; Heisenberg, Carl-Philipp
Article Title: Non-canonical Wnt signalling and regulation of gastrulation movements
Affiliation
Abstract: Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, Patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway similar to that involved in the establishment of planar cell polarity in Drosophila regulates convergent extension movements during zebrafish and Xenopus gastrulation. This finding provides a good starting point to dissect the complex cell biology and genetic regulation of vertebrate gastrulation movements.
Keywords: Xenopus; Zebrafish; Wnt; Convergent extension; Planar polarity
Journal Title: Seminars in Cell & Developmental Biology
Volume: 13
Issue 3
ISSN: 1084-9521
Publisher: Academic Press  
Date Published: 2002-06-01
Start Page: 251
End Page: 260
DOI: 10.1016/S1084-9521(02)00052-6
Open access: no