Beyond TARPs: The growing list of auxiliary AMPAR subunits Review Article


Author(s): Guzman, Segundo J; Jonas, Peter
Title: Beyond TARPs: The growing list of auxiliary AMPAR subunits
Affiliation IST Austria
Abstract: A recent paper by von Engelhardt et al. identifies a novel auxiliary subunit of native AMPARs, termed CKAMP44. Unlike other auxiliary subunits, CKAMP44 accelerates desensitization and prolongs recovery from desensitization. CKAMP44 is highly expressed in hippocampal dentate gyrus granule cells and decreases the paired-pulse ratio at perforant path input synapses. Thus, both principal and auxiliary AMPAR subunits control the time course of signaling at glutamatergic synapses.
Publication Title: Neuron
Volume: 66
Issue 1
ISBN: 0896-6273
Publisher: Elsevier  
Publication Place: United States
Date Published: 2010-04-15
Start Page: 8
End Page: 10
DOI: 10.1016/j.neuron.2010.04.003
Open access: no