Prototype cell-to-cell auxin transport mechanism by intracellular auxin compartmentalization Review Article


Author(s): Wabnik, Krzysztof; Kleine-Vehn, Jürgen; Govaerts, Willy J F; Friml, Jiří
Title: Prototype cell-to-cell auxin transport mechanism by intracellular auxin compartmentalization
Affiliation
Abstract: Carrier-dependent, intercellular auxin transport is central to the developmental patterning of higher plants (tracheophytes). The evolution of this polar auxin transport might be linked to the translocation of some PIN auxin efflux carriers from their presumably ancestral localization at the endoplasmic reticulum (ER) to the polar domains at the plasma membrane. Here we propose an eventually ancient mechanism of intercellular auxin distribution by ER-localized auxin transporters involving intracellular auxin retention and switch-like release from the ER. The proposed model integrates feedback circuits utilizing the conserved nuclear auxin signaling for the regulation of PIN transcription and a hypothetical ER-based signaling for the regulation of PIN-dependent transport activity at the ER. Computer simulations of the model revealed its plausibility for generating auxin channels and localized auxin maxima highlighting the possibility of this alternative mechanism for polar auxin transport. © 2011 Elsevier Ltd.
Keywords: Computer Simulation; Biological Transport; Signal Transduction; Cytoplasm; Receptors, Cell Surface; Indoleacetic Acids; Cell Membrane; Endoplasmic Reticulum; Membrane Transport Proteins; Plant Cells; Plant Proteins
Publication Title: Trends in Plant Science
Volume: 16
Issue 9
ISBN: 1360-1385
Publisher: Cell Press  
Date Published: 2011-09-01
Start Page: 468
End Page: 475
DOI: 10.1016/j.tplants.2011.05.002
Open access: no