Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development Journal Article


Author(s): Mravec, Jozef; Kubeš, Martin; Bielach, Agnieszka; Gaykova, Vassilena; Petrášek, Jan; Skůpa, Petr; Chand, Suresh; Benková, Eva; Zažímalová, Eva; Friml, Jiří
Article Title: Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development
Affiliation
Abstract: The signalling molecule auxin controls plant morphogenesis via its activity gradients, which are produced by intercellular auxin transport. Cellular auxin efflux is the rate-limiting step in this process and depends on PIN and phosphoglycoprotein (PGP) auxin transporters. Mutual roles for these proteins in auxin transport are unclear, as is the significance of their interactions for plant development. Here, we have analysed the importance of the functional interaction between PIN- and PGP-dependent auxin transport in development. We show by analysis of inducible overexpression lines that PINs and PGPs define distinct auxin transport mechanisms: both mediate auxin efflux but they play diverse developmental roles. Components of both systems are expressed during embryogenesis, organogenesis and tropisms, and they interact genetically in both synergistic and antagonistic fashions. A concerted action of PIN- and PGP-dependent efflux systems is required for asymmetric auxin distribution during these processes. We propose a model in which PGP-mediated efflux controls auxin levels in auxin channel-forming cells and, thus, auxin availability for PIN-dependent vectorial auxin movement.
Keywords: Organogenesis; Auxin transport; PIN; Embryogenesis; PGP; Tropisms
Journal Title: Development
Volume: 135
Issue 20
ISSN: 1477-9129
Publisher: Company of Biologists  
Date Published: 2008-10-15
Start Page: 3345
End Page: 3354
DOI: 10.1242/dev.021071
Open access: no