Substance P receptor (NK1)-immunoreactive neurons projecting to the periaqueductal gray: Distribution in the spinal trigeminal nucleus and the spinal cord of the rat Journal Article


Author(s): Li, Jin-Lian; Ding, Yu-Qiang; Xiong, Kang-Hui; Li, Ji-Shuo; Shigemoto, Ryuichi; Mizuno, Noboru
Article Title: Substance P receptor (NK1)-immunoreactive neurons projecting to the periaqueductal gray: Distribution in the spinal trigeminal nucleus and the spinal cord of the rat
Affiliation
Abstract: Substance P receptor (SPR)-immunoreactive neurons projecting to the periaqueductal gray (PAG) were examined in the rat spinal trigeminal nucleus and spinal cord by a retrograde tracing method combined with immunofluorescence histochemistry. After injection of Fluoro-gold (FG) into the PAG, SPR-immunoreactive neurons labeled with FG were observed mainly in the lateral spinal nucleus and lamina I of the medullary and spinal dorsal horns and additionally in laminae V and X of the spinal cord.
Keywords: Immunohistochemistry; Spinal cord; rat; Spinal trigeminal nucleus; Nociception; Double-labeling; Periaqueductal gray; Substance P receptor (NK1)
Journal Title: Neuroscience Research
Volume: 30
Issue 3
ISSN: 0168-0102
Publisher: Elsevier  
Date Published: 1998-03-01
Start Page: 219
End Page: 225
DOI: 10.1016/S0168-0102(97)00132-6
Open access: no