Novel anti-viral therapy: Drugs that block HIV entry at different target sites Journal Article


Author(s): Siegert, Sandra; Schnierle, Peter; Schnierle, Barbara S
Article Title: Novel anti-viral therapy: Drugs that block HIV entry at different target sites
Affiliation
Abstract: Drugs that block the entry of human immunodeficiency virus type 1 (HIV-1) into host cells abrogate the establishment of a productive infection and should ideally diminish the chances of HIV-1 developing resistance. This review will give an overview of the mechanism by which the envelope glycoprotein mediates HIV-1 entry and will summarize current drug developments.
Keywords: Entry; HIV; Inhibitor
Journal Title: Mini-Reviews in Medicinal Chemistry
Volume: 6
Issue 5
ISSN: 13895575
Publisher: Bentham Science Publishers  
Date Published: 2006-05-01
Start Page: 557
End Page: 562
DOI: 10.2174/138955706776876267
Open access: no