Actin rings of power Review Article


Author(s): Schwayer, Cornelia; Sikora, Mateusz; Slovakova, Jana; Kardos, Roland; Heisenberg, Carl-Philipp
Title: Actin rings of power
Affiliation IST Austria
Abstract: Circular or ring-like actin structures play important roles in various developmental and physiological processes. Commonly, these rings are composed of actin filaments and myosin motors (actomyosin) that, upon activation, trigger ring constriction. Actomyosin ring constriction, in turn, has been implicated in key cellular processes ranging from cytokinesis to wound closure. Non-constricting actin ring-like structures also form at cell-cell contacts, where they exert a stabilizing function. Here, we review recent studies on the formation and function of actin ring-like structures in various morphogenetic processes, shedding light on how those different rings have been adapted to fulfill their specific roles.
Publication Title: Developmental Cell
Volume: 37
Issue 6
ISBN: 1534-5807
Publisher: Cell Press  
Date Published: 2016-06-20
Start Page: 493
End Page: 506
DOI: 10.1016/j.devcel.2016.05.024
Open access: no