The physics of development 100 years after D'Arcy Thompson's “on growth and form” Journal Article


Author(s): Briscoe, James; Kicheva, Anna
Article Title: The physics of development 100 years after D'Arcy Thompson's “on growth and form”
Affiliation IST Austria
Abstract: By applying methods and principles from the physical sciences to biological problems, D'Arcy Thompson's On Growth and Form demonstrated how mathematical reasoning reveals elegant, simple explanations for seemingly complex processes. This has had a profound influence on subsequent generations of developmental biologists. We discuss how this influence can be traced through twentieth century morphologists, embryologists and theoreticians to current research that explores the molecular and cellular mechanisms of tissue growth and patterning, including our own studies of the vertebrate neural tube.
Journal Title: Mechanisms of Development
Volume: 145
ISSN: 0925-4773
Publisher: Elsevier  
Date Published: 2017-06-01
Start Page: 26
End Page: 31
URL:
DOI: 10.1016/j.mod.2017.03.005
Notes: JB is supported by the Francis Crick Institute funded by Cancer Research UK (FC001051), the UK Medical Research Council (FC001051), and the Wellcome Trust (FC001051; WT098326MA); AK is supported by IST Austria and by the European Research Council under Horizon 2020 research and innovation programme (680037).
Open access: yes (repository)